Friday Night College Football Prop Bets, Picks, Predictions

  • North Texas's 45 points per game against Charlotte's 128th-ranked scoring offense makes the 26-point football spread and 49ers team total under 16.5 solid betting options.
  • Virginia Tech's Kyron Drones has rushed for touchdowns in four of seven games, while California's Kendrick Raphael has topped 75.5 yards only three times, favoring the anytime touchdown and rushing under props.
  • Boise State's Maddux Madsen has thrown interceptions in just three games with four picks coming against Notre Dame alone, while Nevada's Carter Jones has exceeded 7.5 rush attempts twice in three starts.

RENO, Nev. - The best bets for Friday night's college football slate feature North Texas's explosive offense against Charlotte's struggling defense, California's ground game facing Virginia Tech's defensive front, and Boise State's ball security against Nevada's turnover-challenged defense.

North Texas Mean Green vs Charlotte 49ers

North Texas averages 45 points per game behind quarterback Drew Mestemaker, who has thrown for 17 touchdowns with just three interceptions. The Mean Green lead the FBS in scoring, while Charlotte's defense ranks 128th nationally in scoring offense allowed, giving up nearly 35 points per game.

This spread at -110 odds combines North Texas's offensive firepower with Charlotte's defensive struggles as the 49ers arrive under first-year coach Tim Albin with quarterback instability.

Best Prop Bets For Mean Green vs 49ers

  • Spread: North Texas -26 at -110
  • Team Total: Charlotte Under 16.5 at -110

With the Mean Green averaging over 270 rushing yards last week in a 55-17 win over UTSA, this matchup should favor the road team throughout at legal sports betting sites. The team total under 16.5 at -110 odds is a solid bet because Charlotte has had offensive difficulties the whole season and has frequently played from behind.

The Mean Green demonstrated their ability to dominate with running back Caleb Hawkins leading a balanced offensive attack. Charlotte's incapacity to match North Texas's explosive scoring capabilities against high-powered offenses should be noted by those interested in college football prop bets.

California Bears vs Virginia Tech Hokies

With -110 odds, Virginia Tech quarterback Kyron Drones's red-zone rushing ability and California's struggling ground game against strong defenses present advantageous betting options.

Drones has rushed for five touchdowns this season, scoring in four of seven games, while California's freshman running back Kendrick Raphael has topped 75.5 rushing yards only three times.

Best Prop Bets For Golden Bears vs Hokies

  • Anytime Touchdown: Kyron Drones at -176
  • Rushing Yards: Kendrick Raphael Under 75.5 at -115

Given that Virginia Tech's defensive front will likely force Cal to rely more on their passing attack, Raphael's rushing under at -115 odds makes sense. Due to the freshman's inconsistent play throughout the season, this contest is a good bargain at California sportsbooks that have CFB props.

Boise State Broncos vs Nevada Wolf Pack

Boise State quarterback Maddux Madsen has thrown interceptions in just three games this season, with four of his six picks coming against Notre Dame. The Broncos visit Nevada as heavy favorites, while the Wolf Pack struggle to create turnovers defensively.

Best Prop Bets For Broncos vs Wolf Pack

  • Interceptions: Maddux Madsen Under 0.5 at -180
  • Rush Attempts: Carter Jones Over 7.5 at -110

Nevada's Carter Jones has exceeded 7.5 rushing attempts twice in three starts, proving the Wolf Pack's commitment to controlling tempo through their ground game. At home against Boise State's disciplined offense, Nevada should lean heavily on their running back.

At -180 odds, Madsen's interception under reflects his ball security against a defense that rarely forces turnovers. The over on Jones's rush attempts at -110 odds capitalizes on Nevada's run-heavy game plan throughout the season.

About Hunter Gold

Hunter is a college football enthusiast who's been on the CollegeFootballProps.com team since 2025. He grew up a Florida State fan and just recently graduated as a Nole earlier in 2025. When he's not analyzing the latest Seminoles matchups, he's following up on the top college stars and picking up a game of College Football 25.