- Alabama is a 6-point favorite against Mississippi State in Week 5.
- Alabama and Mississippi State are both 4-0 coming in.
STARKVILLE, Miss. – Mississippi State has jumped into the top-25 for the first time in 2022, matching their highest ranking at #16. Now in Week 5, the Bulldogs face their biggest game of the season as they host the #7 Alabama Crimson Tide.
SEC NATION IS COMING TO STARKVEGAS ‼️
No. 7 @AlabamaFTBL at No. 16 @HailStateFB
See y’all Saturday in The Junction 🔔 pic.twitter.com/fyUlFcu0ZV— SEC Network (@SECNetwork) September 28, 2026
College football prop betting sites are leaning on Alabama on the road here with just under a touchdown margin on the spread. Mississippi State does have a strong argument as one of the best offenses in the SEC to this point.
Alabama Vs. Mississippi State Betting Lines
- Moneyline: Alabama (-225) vs. Mississippi State (+185)
- Spread: Alabama -6 (-105)
- Total: 60
A Case For Mississippi State?
There is absolutely a strong case to make on Mississippi sportsbooks in favor of the Bulldogs. Mississippi State comes in undefeated and averaging an SEC-high 533.3 yards per game to go along with 43 points. What separates Mississippi State from the rest of the conference is their strength of schedule coming in. They’ve played three Power Conference opponents as well as a top-20 opponent and outscored them 110-71.
For Alabama, while they do look strong at 4-0 with a top-ranked defense in the SEC, they have had scares coming in. Against both Kentucky and Florida State in two of the last three weeks, the Tide found themselves down early before comeback wins in the second half.
An early deficit against this explosive Mississippi State team could be too much for them to come back from. Mississippi State is an undefeated 4-0 against the spread this season and is covering by +22.5 points on average.
