- Ohio State is a 14-point favorite against Iowa.
- There is a 45.5-point total set for the game.
IOWA CITY, Iowa – College GameDay is headed to Kinnick Stadium in Iowa City for a top-15 matchup between the #5 Ohio State Buckeyes and #14 Iowa Hawkeyes. Ohio State is a two-touchdown favorite.
FOR THE FIRST TIME IN 20 YEARS WE ARE HEADED TO IOWA CITY!
After a dramatic win last night, we couldn’t miss @HawkeyeFootball‘s showdown with Ohio State on Saturday 👏
See you there📍 pic.twitter.com/z5xCyDVOpq— College GameDay (@CollegeGameDay) September 27, 2026
College football prop betting sites are laying 14 points to Ohio State. Despite both teams being top-5 defenses in the Big Ten, there is still a slightly higher 45.5-point total.
Ohio State Vs. Iowa Betting Lines
- Moneyline: Ohio State (-650) vs. Iowa (+450)
- Spread: Ohio State -14 (-115)
- Total: 45.5
Hard Lean On The Under
If there was ever a game on college football sportsbooks that screamed the under, it’s this one. Regardless of what Ohio State’s offense has done. Both of these defenses are top-5 in the Big Ten. Iowa leads the conference in allowing just 8 points per game, while Ohio State isn’t far behind at 12.3 points allowed.
One of the biggest tells that this one could lean under is the Iowa secondary, which is fourth in the conference in allowing just 152 pass yards per game. This could play a major factor in both Julian Sayin and Jeremiah Smith’s performances.
Ohio State will play its part as well, allowing just under 115 rush yards per game. Iowa’s run game is one of the best in the Big Ten at 215.5 yards per game.
